A newsstand vendor takes a customer's cash for tickets in Tuesday's Mega Millions and Wednesday's Powerball lottery drawings in New York City, New York, U.S., October 23, 2018.
A $750 million jackpot, the fourth largest in U.S. history and the second astronomical jackpot this week, will be at stake during the Powerball drawing on Saturday.
The drawing will be held at 11 p.m. EST.
It comes after one ticket sold in South Carolina matched all six numbers on Tuesday in the United States' other main lottery, the Mega Millions, to win a jackpot of $1.537 billion, just short of a world record.
No one has come forward to claim the Mega Millions prize.
One ticket sold in South Carolina matched all six numbers in the Mega Millions lottery draw on Tuesday for a record setting $1.6 billion jackpot, the state's lottery said on its website early on Wednesday.The ticket matched the five numbers 5, 28, 62, 65, 70 and the Mega Ball 5 that were drawn on Tuesday night. Anyone who hit all six numbers to win the jackpot can choose an immediate cash payment of $904 million or receive the $1.6 billion prize over 29 years.It was unclear early on Wednesday if other winning tickets were sold elsewhere.The website of the South Carolina Education Lottery showed that one winning ticket was sold in the state. The buyer of the ticket beat odds of 1 in 303 million to win the Mega Millions drawing.Mega Millions set a record for lottery jackpots after nobody won the $1 billion prize on Friday. The previous record was a $1.586 billion jackpot for a Powerball drawing in 2016. 
One winning ticket sold in South Carolina for $1.6 bln lottery jackpot
If someone wins the Powerball on Saturday they will have the option of an immediate cash payment of $428.6 million, or the $750 million prize paid out over 29 years, according to the lottery.
The Powerball jackpot has rolled over since it was last won in August, the lottery said. Powerball lottery tickets are sold in 44 states, Washington D.C., Puerto Rico and the U.S. Virgin Islands.
The odds of matching all five numbers and the Powerball is 1 in 292 million.
States receive a percentage of lottery ticket sales and use the money to support public schools or to meet other needs.
Who wants to be a billionaire?For $2 a ticket, you have chance to be among the richest people in the world if you beat the longshot odds of 1 in 303 million to win the Mega Millions lottery jackpot of $1.6 billion Tuesday night.The sum reached a world record for lottery jackpots after there were no winners claimed a $1 billion prize on Friday.It is so much money that if you took the instant cash payout in $100 bills, you could make a stack over 3,200 feet (975 meters) taller than any building in the world, the lottery's website said."Mega Millions has already entered historic territory, but it's truly astounding to think that now the jackpot has reached an all-time world record," Gordon Medenica, lead director of the Mega Millions Group, said in a statement.But you are more likely to get killed by a shark than win, with odds of a shark attack at 1 in 3.7 million, according the Tucson, Arizona-based International Wildlife Museum.After taxes, the cash value of the Mega Millions prize will be an estimated $904 million, which is greater than the gross domestic product of countries including South Africa, Columbia and Switzerland, according to 2017 figures from the World Bank.Wednesday's Powerball lottery prize stands at an estimated $620 million, making it the fifth largest jackpot in U.S. history, officals said, after no one got all six numbers in Saturday's drawing.The lump sum cash payout is estimated at $354.3 million.The current Mega Millions jackpot beats the previous record, a $1.586 billion jackpot for a Powerball drawing in 2016, said Seth Elkin, a spokesman for Mega Millions.If there is more than one winner, the jackpot would be shared, as happened when the previous Mega Millions record of $656 million was drawn in March 2012 and was divided between winners in Kansas, Illinois and Maryland, a lottery official said.
US lottery jackpots climb to $2.2 billion combined after no winners